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People want to provide obesity care to their employees, but they want to do it in a way that doesnt bankrupt them. For patients, it may just be too tough to stay on the medications indefinitely, the review found

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Hepatic laboratory testing is recommended for all patients and the drug may need to be discontinued if alanine transaminase levels hit 10 times the high end of the normal range or liver inflammation develops

Non-GLP-1 agents are most appropriate for patients unable to tolerate GLP-1 medications, those with GLP-1 contraindications (such as personal or family history of medullary thyroid carcinoma), or individuals requiring different metabolic pathways